Does Vitamin D Influence the Ovarian Reserve in InfertileWomen-A Short Communication by
Kulvinder Kochar Kaur in Open Access Journal of Reproductive System and Sexual Disorders in Lupine_Publishers.
Kulvinder Kochar Kaur in Open Access Journal of Reproductive System and Sexual Disorders in Lupine_Publishers.
Calcium homeostasis and bone density are 2 important
functions of Vitamin D in human beings. To mediate its biologic
functions, it utilizes Vitamin D receptors, that are present mostly in
calcium regulating tissues like the bone and parathyroid glands [1].
Still finding Vitamin D receptors within the reproductive tissues like
the ovary, endometrium, testis. Hypothalamus along with pituitary
has stimulated the study of Vitamin D’s role in human reproduction
[1]. Previous studies showed that Vitamin D can change the
antimullerian hormone (AMH) signaling, follicle stimulating
hormone (FSH) sensitivity and progesterone (P) Production and
release in human granulose cells as per Irani M and Merhi Z [1].
Moreover, recently Chu et al 2018 carried out a systematic review
and meta-analysis in women who were undergoing assisted
reproduction showed that women having enough Vitamin D had
>odds of getting a live birth (odds ratio 1.33) as compared to those
who had deficient Vitamin D levels [2]. Hence with the presence
of Vitamin D deficiency world over within women of reproductive
age, it is imperative to study the effect of Vitamin D deficiency on
ovarian physiology.
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