Monday, February 18, 2019

Reproductive Journals-Lupine Publishers- Luteal Phase Support using Oral Dydrogesterone-a Prospective Treatment for Future Replacing Micronized Vaginal Progesterone: (OAJRSD)








Although micronized vaginal progesterone is the accepted norm for use in luteal phase support (LPS) in controlled ovarian stimulation (COS) that is used for in vitro fertilization (IVF) cycles, recently importance of oral Dydrogesterone has got the importance in lieu of its oral availability, cheap, no cumbersome side effects and no definitive newer fetal side effects. After the LOTUS 1 trial with a multicenter double placebo, double dummy design it has proved an equal efficacy if not superiority of oral D, over micronized vaginal progesterone and it seems D might soon become the standard of care for LPS in conventional IVF cycles besides its routine indication for recurrent abortions.



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Monday, February 4, 2019

Reproductive Medicine Research Journals-Lupine Publishers-Systemic Lupus Erythematosus: Reproductive Risks and Choices: (OAJRSD)







In ancient times, lupus means a disease that eats away, bites and destroys the skin and various organs. The Lupus Foundation of America estimates that 1.5 million Americans, and at least five million people worldwide, have a form of lupus. [1] There are four types of lupus accepted and they are Systemic lupus, cutaneous lupus, drug-induced lupus (mainly by drugs like hydralazine, Isoniazid.) and neonatal lupus. Systemic lupus accounts for approximately 70 percent of all cases of lupus [2]. It is a well-known autoimmune disease. It occurs predominantly in females in a varied ratio of 5 to10:1 according to previous studies. The course of the disease is a chronic, relapsing and remitting in nature. Its popularity among the autoimmune disease is its occurrence in reproductive aged women with multisystem involvement affecting the woman’s reproductive life as well as its potential fatality.


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