Luteal Phase Support using Oral Dydrogesterone-a Prospective Treatment for Future Replacing Micronized Vaginal Progesterone by Kulvinder Kochar Kaur in Open Access Journal of Reproductive System and Sexual Disorders (OAJRSD) in Lupine Publishers
Although
micronized vaginal progesterone is the accepted norm for use in luteal phase
support (LPS) in controlled ovarian stimulation (COS) that is used for in vitro
fertilization (IVF) cycles, recently importance of oral Dydrogesterone has got
the importance in lieu of its oral availability, cheap, no cumbersome side
effects and no definitive newer fetal side effects. After the LOTUS 1 trial
with a multicenter double placebo, double dummy design it has proved an equal
efficacy if not superiority of oral D, over micronized vaginal progesterone and
it seems D might soon become the standard of care for LPS in conventional IVF
cycles besides its routine indication for recurrent abortions.
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