Open Access Journal of Reproductive System and Sexual Disorders (OAJRSD) in Lupine Publishers
Selective
Androgen Receptor Modulators (SARMs) were discovered in the late 1990’s.They
may have an application in treatments of various diseases, including muscle
wasting, cancer cachexia, breast cancer, osteoporosis, andropause and
sarcopenia. In this minireview the development, pharmacodynamics, and the phase
1 and 2 trial results of the SARMs are discussed with a special emphasis on the
illicit use of the SARMs.
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